allodynia from glp 1 GLP-1 and its derived peptides mediate pain relief through direct TRPV1 inhibition without affecting thermoregulation allodynia and glp 1 is

10.1016/S2468-1253(19)30089-5 Lancet Gastroenterol

Suner SS, Bhethanabotla VR, Ayyala RS, Sahiner N

This is different from a compounded formula, which is not FDA approved and where little research currently exists surrounding safety and efficacy.53 Patients using compounded versions may not receive a standardized dose, and safety and efficacy data for these products is currently lacking

Key benefits of MOTS-c include: Improved metabolic flexibility and insulin sensitivity Support for weight management and fat oxidation Potential anti-aging effects by reducing oxidative stress Enhanced endurance and muscle recovery in some studies

None of that is a failure of effort

DIABETES DRUGS Market Overview, by Drug Class Segment 49 13.1.1