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John Horneff, an associate professor of orthopedic surgery at the University of Pennsylvania and the lead author of the study, told NBC News

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In addition, immigration contributed very few patients with genotypes 1a and 4, confirming that in our area it is the infection among the native population that explains the increase in genotype 4, mainly linked to the IDU

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We used the force field parameters for single-protonated phosphorylated Ser (S1P) and Thr (T1P) residues developed by Sticht and co-workers 59

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