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Shared decision-making : If considering offlabel or prevention use, open discussion of uncertain benefit, possible side effects, cost, monitoring is essential

Patients with T2D with stable CAD presented an improvement in endothelial function expressed by an increase in flow-mediated vasodilation of the brachial artery, independent of changes in systolic and diastolic blood pressure during a hyperinsulinemic clamp in response to GLP-1 [35]

Diabetes Ther (2024).

Metformin, one of the most widely used diabetes drugs, has also been studied for its potential to protect the brain and reduce dementia risk

The effects can be experienced within the first few days, whether thats an effect on your appetite or side effects like nausea, vomiting or diarrhea. These two new drugs are part of a larger class of GLP-1 drugs that mimic the gut hormone GLP-1, which is made naturally in your intestines and brain

Its small-molecule structure allows for consistent absorption regardless of stomach contents