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In particular, the suboptimal pharmacokinetics and pharmacodynamics of these compounds and their poor ability to cross the BBB could represent considerable obstacles for a significant therapeutic efficacy

Once a vial has been pierced and drawn from, standard laboratory practice typically allows continued use for up to 28 days, after which the vial should be discarded

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doi: 10.1186/s13075-024-03423-5 11 WjcikPGgotekAarkoviNSkrzydlewskaE

For patients whose obesity-related comorbidities have not fully resolved after surgery or have recurred with weight regain, these medications may provide additional therapeutic value

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