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The weight regain observed after the discontinuation of currently approved GLP-1 and GIP/GLP-1 receptor agonists represents an unmet need for anti-obesity regimens with sustained efficacy

On its official website, Refills advertises outcomes and access metrics such as "92% of patients report improved energy," "3x faster weight loss compared to lifestyle changes alone," nationwide access, and more than 10,000 personalized plans

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The company states it does not currently serve Alabama, Alaska, Arkansas, Hawaii, Massachusetts, Missouri, New Mexico, New York, South Carolina, or Virginia, and notes it is "working to expand availability to more states." State availability may change

22, 23 Furthermore, GLP-1 receptors in this region and in the ventral tegmental area appear to be responsible for an inhibitory effect of GLP-1 on the rewarding value of food in rats

First, Maximus is explicit that compounded semaglutide is not an FDAapproved drug, even when shipped from reputable pharmacies