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Considering that very little is known about the local and temporal concentrations of NADPH and TGR and the multiple redox-associated conformational states, it is difficult to assess how accurately the biochemical assay with recombinant TGR models the inhibition of TGR in worms ex vivo or in vivo

Curr Pediatr Rep

SeMet can also be metabolised via the multi-step trans-sulfuration pathway to selenocysteine, in turn degraded to hydrogen selenide for subsequent methylation by methyltransferases that give rise to methylselenol (Fig

Li J, Zheng C, Zhang L, Hong C, Liu X, Zhang X, et al

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