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Healthcare professionals are asked to report Yellow Cards on behalf of patients who are taking GLP-1 medicines (including dual GLP-1 and GIP agonists) and experience acute pancreatitis

Some research also suggests potential benefits for conditions such as fatty liver disease and obstructive sleep apnea

Endocrinol 151, 1520 (2010) John, H

These are metabolic sequelae, and they are largely preventable with appropriate intervention

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According to FDA prescribing information, these include: Nausea (occurring in 1544% of patients depending on formulation and dose) Vomiting (524% of patients) Diarrhea (830% of patients) Abdominal pain (511% of patients) Constipation (324% of patients) These gastrointestinal symptoms typically emerge during dose escalation and often diminish over time as physiological tolerance develops