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Future research should focus on large-scale, well-controlled randomized trials with standardized dosing protocols, clearly defined deficiency thresholds, and long-term follow-up to strengthen the evidence base and guide clinical practice

2 additional categories are analyzed in the full comparison

While the mechanisms are unknown, it is believed folic acid plays a role in disrupting the DNA damage process

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This distinction proves important as appropriate inflammatory response is necessary for healing, but excessive or prolonged inflammation impairs recovery

Retrieved 6 January 2020