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[3] The practical result of that research is a molecule that behaves very differently from native IGF-1 in laboratory systems, and that has since become a widely stocked reagent for cell-culture applications

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The newer agents have been associated with weight loss of 15 to 20% of bodyweight, which approaches that seen with bariatric surgery

Published studies by Blum & Bhatt (2003) and others have utilized IGF-1 LR3 as a critical component in defined media for embryonic stem cell and induced pluripotent stem cell (iPSC) maintenance