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Palmitoylation is a reversible lipid modification where palmitate is covalently attached to cysteine residues through a thioester bond, which can significantly increase the hydrophobicity of proteins, thereby affecting their affinity for membrane structures, their membrane localization, protein-protein interactions, and signal transduction of the protein [60, 61]

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But, when that is not enough, you can always opt for man-made forms like Glutathione peptide

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