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The same researchers conducted a larger intervention in 42 children with autistic disorder who had evidence of reduced methylation capacity or GSH:GSSG in which they were supplemented with folinic acid and methyl-cobalamin for 3 months [48]

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In the case of MS, while axonal and neuronal destruction is the ultimate fate and cause of disability in disease, glia is present in inflammation (microglia), myelin loss and tentative regeneration (oligodendrocyte) and synaptopathy itself (astrocytes)

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[DOI] [PubMed] [Google Scholar] 70.Ikemoto F, Song G, Tominaga M, Yamamoto K