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Laminin-5 and MMP upregulation TB4 induces expression of matrix metalloproteinases (MMP-2, MMP-9) that remodel extracellular matrix during healing (Malinda 1999 J Invest Dermatol)

Somatic instability of the FGF14-SCA27B GAATTC repeat reveals a marked expansion bias in the cerebellum

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FDA Label Novo Nordisk

Shaking the vial can shear these chains, rendering the compound useless