Importantly there are no currently reported SNPs in Nrf2 which impact on its function
However, glutathione production declines with age , and factors like poor diet, high stress, alcohol consumption, and exposure to toxins further deplete levels
This decline is associated with accelerated aging, impaired detoxification, weakened immunity, increased cancer risk, neurodegeneration, and reduced athletic performance and recovery
In this particular case, cysteine is severely depleted, and NAC helps to restore cellular glutathione levels to homeostasis by providing a source of cysteine
Coffee Consumption, Cancer, and Healthy Aging: Epidemiological Evidence and Underlying Mechanisms
This guide focuses on the questions that matter when buying a glutathione supplement: What form and amount does it contain