There is strong evidence that GLP-1 medications can: Improve HbA1c and blood glucose control Support appetite regulation Improve cardiovascular risk markers in some populations Support improvements in cholesterol and triglycerides Lower blood pressure (modestly) Reduce risk of major cardiovascular events in higher-risk individuals For many people, these changes occur independently of weight reduction and are linked to improved metabolic functioning
Think of GLP-1 as your body's "meal manager." The moment you start eating, your gut starts releasing this hormone
Within 12 months of stopping, 27% had switched to a different medication, 20% restarted their original medication, 14% continued with lifestyle modification supported by professionals, and less than 1% pursued bariatric surgery
Diabetes Obes Metab (2014) 16(9):85060
Sitagliptin Attenuates the Progression of Carotid Intima-Media Thickening in Insulin-Treated Patients With Type 2 Diabetes: The Sitagliptin Preventive Study of Intima-Media Thickness Evaluation (SPIKE): A Randomized Controlled Trial
Where GLP-1 therapy may be useful in a brain-health plan For selected patients, GLP-1 therapy may support brain health indirectly by improving the systems that influence cognitive risk
