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GLP-1 medications slow gastric emptying and increase insulin secretion in response to food, helping regulate post-meal glucose spikes

The MHRA safety guidance emphasises that GLP-1 receptor agonists should only be used under medical supervision with appropriate monitoring

Risks of muscle loss, malignancy or prerenal acute kidney injury appear negligible from analysis of currently available datasets

Official guidance from professional organizations often reflects the best consensus on evidence interpretation

Just over half (56%) of GLP-1 users including 55% of those with health insurance say it was difficult to afford these drugs, including one in four who say it was very difficult. The cost of the medications as well as side effects are the most common reason given for discontinuing GLP-1 use

Weight Watchers now sells those same drugs, having pivoted into telehealth with the acquisition of Sequence last year