Furthermore, -syn has a mitochondrial targeting sequence (MTS) at the N-terminal and is localized to the outer mitochondrial membrane (OMM), intermembrane space (IMS), inner mitochondrial membrane (IMM) (Vicario et al., 2019)
Koeberle SC, Kipp AP, Stuppner H, Koeberle A (2023) Ferroptosis-modulating small molecules for targeting drug-resistant cancer: Challenges and opportunities in manipulating redox signaling
Autoimmune supplements such as glutathione, curcumin, resveratrol, and L-glutamine help address nutrient deficiencies common in autoimmune conditions due to chronic inflammation and impaired nutrient absorption
This mechanism may explain the inhibition of the enzyme activity of several enzymes with essential catalytic or regulatory thiol groups by the thiol binding metals
B12 has a very low toxicity, so large amounts are not considered dangerous
doi:10.1007/s10815-021-02247-5