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Among three human CML blast-crisis lines, K562 cells are most sensitive to JMF4073

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Six randomized, double-blind, placebo-controlled trials involving over 900 participants demonstrated that this growth hormone fragment peptide is well-tolerated with a safety profile indistinguishable from placebo

The trade-off is twice as many injections and slightly more complex scheduling

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At the time, it said there was limited evidence surrounding their therapeutic benefit and maintained there were safety concerns, potential for abuse, and not enough suitably trained psychiatrists to warrant the rescheduling