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Side effects and patient compliance are important, with as many as 10% discontinuing treatment because of them

He added: "Further studies are needed to test our hypothesis

Liang S, Yu J, Zhao M et al (2024) In vitro digestion and fecal fermentation of selenocompounds: impact on gut microbiota, antioxidant activity, and short-chain fatty acids

This essential trace mineral plays a vital role in carbohydrate metabolism, helping to minimize the blood sugar spikes and crashes that often trigger hunger and overeating

They have other downsides too

Given the high cost of GLP-1s, the patients in that arm of the study may also have had greater access to resources (exercise programs, health coaches, and nutritionists), she says