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When this happens, some people experience reflux, or heartburn while others have absolutely no symptoms

Weight loss is caused because patients simply eat much less

Surprisingly though, a second-generation GLP-1RA conjugate composed of vitamin B12 and exendin-4 was reported to reduce the adverse reactions, exhibiting improved tolerance (230)

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However, the immediate barriers to adoption of these drugs may lie not in their side effect profile, but rather in the ability of our physicians and healthcare system to accept them