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There were 31 patients who had at least 1 immune-related adverse event (immune-related adverse events group), whereas the remaining 109 patients had no immune-related adverse events (no immune-related adverse events group)

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Addison's Disease Hyperpigmentation On Tongue Addison's disease - primary adrenal insufficiency - is one of the most clinically significant causes of tongue hyperpigmentation because the oral finding can be a visible clue that leads directly to a life-changing (and potentially life-saving) diagnosis

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Juturu V, Bowman JP, Deshpande J