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This complete absence of tolerability-driven discontinuations indicates that even when side effects occurred, they were sufficiently mild that participants chose to continue treatment

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You may also notice some skin tightness and mild sensitivity to touch

A 2021 peer-reviewed review of NNMT in obesity and type 2 diabetes states explicitly that 'clinical trials targeting NNMT have not been reported' meaning every quantitative efficacy figure available for this compound comes from mice, and there is currently zero published human efficacy data