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The aging-associated enzyme CLK-1 is a member of the carboxylate-bridged diiron family of proteins

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Methods We looked at a subset of the Truveta Data from January 2021 to September 2025 to identify two patient cohorts

A 2016 contemporary meta-analysis of randomized controlled trials of probiotic supplementation found that short-term probiotic consumption decreased intestinal transit time with consistently greater treatment effects in constipated adults, older adults, and with certain probiotic strains.[5] The effect size at the category level is modest, and the heterogeneity across included trials is substantial