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Especially in type 2 diabetes, any change in treatment should always take place under medical supervision

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One major limitation is the incomplete knowledge of the metabolic pathways and transformations that polyphenols undergo after ingestion, particularly due to interactions with the gut microbiome and the formation of diverse metabolites whose biological activities are not well characterized (119)

Knowing that exercise is so important, if someone says, I dont even feel like working out anymore when Im on this medicine, that, to me, is a problem. McGowan advised patients to report any emotional symptoms to their doctor