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Before regulatory changes, NMN led the anti-aging supplement market with nearly 300 different brands available on Amazon alone, while NAD+ had about 40 brands [8]

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As soon as Novo Nordisks two semaglutide offerings, Ozempic and Wegovy, scored FDA approval as obesity treatments in 2021, demand for this entire class of drugs skyrocketed

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revealed that prolonged intake (90 days) of high concentrations of green tea catechins (5%) brought about hepatotoxic effects in male rats by the increased levels of ALT and AST 48 , which could suggest that the use isolated or pure polyphenols could be detrimental to the functioning of these organs