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Proglucagon, a precursor to both glucagon and GLP-1 is synthesized in alpha-cells of the pancreas, intestinal L-cells, and specific neurons in the hindbrain

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In particular, the extraintestinal spread of luminal microbes possessing components with structural similarity to those of the human host are thought to be involved in the breakdown of immune tolerance towards host components

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The research team added, "While dreams occur in various stages of sleep, many of their functions remain unknown," and that their work "offers a new perspective for understanding sleep health and mental health." 10.1371/journal.pbio.3003683