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[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Del Prato S., Kahn S

Outcomes were similar to those who remained on GLP-1 therapy, and most participants maintained HbA1c below the diagnostic threshold for diabetes

Why Post-Approval Data Is the Most Commercially Valuable and Most Legally Vulnerable New Matter Post-approval discoveries new dosing regimens validated in Phase IV trials, new patient sub-populations identified through real-world evidence, device improvements incorporated into combination product submissions generate some of the highest-value secondary patents in pharmaceutical portfolios

For gut-related goals , improvements often take longer

A gap of only 12 hours might give unreliable results

Data were assessed with one-way analysis of variance (ANOVA) and then by Tukey's test for comparison between model and treatment groups