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Surgical procedures or conditions that affect the gut, such as gastric bypass surgery or celiac disease, can prevent intrinsic factors from binding to B12 and prevent the body from breaking it down before absorbing the vitamin

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Both conditions (hypothyroidism and diabetes) affect large segments of the population, so their treatments rank very high in prescription counts

True anaphylaxis to B12 is extremely rare but has been documented in medical literature

[1] [4] As a precaution, glutathione injection should be avoided during pregnancy unless the potential benefits clearly outweigh the risks and only under the supervision of a qualified healthcare provider

When combining peptides, starting with conservative doses and gradually adjusting based on response is advisable