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After a 5-min incubation at RT, 3.75 l of the appropriate 0.3 M ssDNA repair template was added and incubated for another 5 min

Among the patients who develop NASH, 1020% will progress to higher-grade fibrosis and approximately 5% will develop overt cirrhosis (1) ( Figure 1 Triglycerides (TG) accumulation is likely one of the first steps in the pathophysiology of NAFLD as a result of an impaired free fatty acid (FFA) metabolism in the liver (Figure 2)