This review aims to dissect the epidemiological and mechanistic links between altered metabolism and HCC across MASLD, ALD, and viral etiologies, summarize the current therapeutic landscape, and critically evaluate the emerging role of GLP-1 RAs as a strategic intervention for prevention and clinical management across this complex disease spectrum
Constipation is common with weight loss and should be managed proactively
Suppression and blocking of the male hormone testosterone leads to the suppression of male sexual characteristics, and spironolactone is the most commonly used androgen blocker
The bottom line Common side effects of glucagon-like peptide-1 (GLP-1) medications include nausea and vomiting, stomach pain, and diarrhea
The hypertensive effects of DPP-4i may be diminished by agents that block the SNS and enhanced by hypotensive agents with no effect on the SNS (86)
Remember that most people taking GLP-1 medications experience no vision problems , particularly when appropriate monitoring and gradual glycaemic improvement are implemented
