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For others, it means the morning effect is too slow

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Paton, J

reported that the administration of liraglutide to HFD mice reduced body weight, glucose, LFTs, histologically-confirmed hepatic steatosis, and bridging fibrosis after 2 weeks of treatment

This means that despite having high levels of leptin, their brains do not receive the signal to stop eating, leading to continued weight gain

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