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The addition of GIP receptor agonism in tirzepatide does not appear to significantly amplify heart rate effects compared to GLP-1-only drugs like semaglutide

A real-world study published in JAMA Internal Medicine found that patients taking Mounjaro achieved greater weight loss and were more likely to hit weight-loss benchmarks compared to those taking Ozempic

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The activation of glutathione peroxidase enhances the clearance of ROS in cancer cells (Jin et al., 2015)