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64 Furthermore, in mice, the imbalance of gut microbiota that occurs in obesity reduces the expression of GLP-1Rs
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TMAO also induces reactive oxygen species through oxidative stress, altering the invasion and migration of tumour cells, thereby affecting CRC progression (Subramaniam and Fletcher, 2018)
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Bone loss during the fat loss period (fat loss model in obese rats) Experimental Design: Animals: Obese SD rats induced by high-fat diet were randomly divided into an obesity control group, a simple weight loss group (30% calorie restriction), and a weight loss+AOD 9604 group (500 g/kg/day)
