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Data were analyzed using one-way ANOVA, followed by Tukeys test for a and b (right panel) and two-way ANOVA, followed by Tukeys test for b (left panel)

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Liver tissues were isolated from animals and total glutathione levels were measured

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SG-55 increases the ratio of reduced/ oxidized nicotinamide adenine dinucleotide phosphate (NADPH/NADP + ), decreases the ratio of reduced/ oxidized glutathione (GSH/GSSG), and induces DNA double-strand breaks