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The overexpression of miR-21 in UC-MSCs may play a critical role in the restoration of ovarian function in ZP3 peptide-induced autoimmune POI mice, potentially through inhibition of the phosphatase and tensin homolog /Akt/ forkhead box O3a (PTEN/Akt/FOXO3a) signaling pathway
Small extracellular vesicles from human adipose-derived stem cells attenuate cartilage degeneration
Existing evidence suggests that this approach is safe, compatible with other therapeutic modalities, and represents a novel avenue for the treatment of solid tumors
S.WhiteJ
Riddell J, Shuman EM
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