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Dysfunction or disruption of the redox buffer has been implicated in various diseases and the implications make GSH, GSSG, and their related systems valid and effective targets for medicinal chemistry interventions

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A food-born heterocyclic amine, 2-amino-1-methyl-6-phenylimidazo[4,5- b ]pyridine (PhIP), suppresses tumor necrosis factor- expression in lipoteichoic acid-stimulated RAW 264.7 cells

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However, the transient passage of food through the oesophagus would probably not allow sufficient time for the carcinogenic event to occur

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