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It helps maintain healthy cholesterol and blood sugar levels, as well as GI microbial balance

[1] [2] This once-weekly subcutaneous injection works by enhancing insulin secretion in response to meals, suppressing glucagon release, slowing gastric emptying, and reducing appetite through central nervous system pathways

In essence, GL acts as a prodrug that requires enzymatic conversion to its active metabolite, GA, which then undergoes extensive enterohepatic circulation

Tirzepatide affects blood sugar, metabolic markers, and pancreatic function

In the clinic, we often aim for gradual weight loss with adequate protein and micronutrient intake

It's important to understand how GLP-1's may interact with these substances