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Seek prompt non-emergency advice if you experience unexplained rapid weight gain of approximately 2 kg or more within three days, a consistent upward trend over several weeks, or new symptoms such as persistent fatigue, cold intolerance, or irregular periods

In the U.S., CVD is the leading cause of death, constitutes 17% of healthcare costs, and is estimated to increase in prevalence by ~10% and direct costs by almost three-fold over the next 20 years under current CVD prevention and treatment regimes [2]

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