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Introduction Rheumatoid Arthritis (RA) is a chronic immune-mediated inflammatory disorder that involves the synovial membranes of multiple joints (Sewell and Trentham, 1993

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In a close similarity with the results obtained for -tocotrienols in the post-ischemic brain (Park et al., 2011), -tocotrienols protect mouse hippocampal and cortical neurons from cell death via modulation of neurodegenerative signaling cascades, and thereby preserve the function of that brain area (Ambrogini et al., 2010) and Sen et al

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Research is also studying the peptides effects on immune function and its possible uses in immunology research

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Dysbiosis in the gut microbiota composition has been implicated in various neuropsychiatric and neurodegenerative disorders, such as depression, anxiety, autism spectrum disorder, Parkinsons disease and Alzheimers disease [128,129,130,131,132,133]

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