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Overall risk of bias for each trial was considered low if all domains were at low risk of bias, and high if at least one domain was at high risk of bias

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Sources: Research on berberine indicates several notable benefits and effects: Blood Sugar Regulation : Berberine significantly lowers blood glucose levels, akin to the effects of prescription medications like Metformin

Metformin commonly causes digestive effects, especially nausea, diarrhea, gas, or abdominal discomfort

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Each plays a distinct role