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There are several chemical labeling methods including isotope-coded affinity tag (ICAT), isobaric tags for relative and absolute quantitation (iTRAQ), mass differential tags for relative and absolute quantification (mTRAQ) and stable isotope labeling by amino acids in cell culture (SILAC) to aid the analytical process

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Materials and Methods Participants The current study protocol was approved by the Institutional Review Board at the University of North Texas and all aspects of the study were conducted in accordance with the Declaration of Helsinki

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