These authors indicate that the increased ROS content in the liver seems to be the consequence of both a deficient antioxidant defense and a stimulated pro-oxidant system (136)
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Braylee Wardwell, PharmD PGY2 Ambulatory Care Resident UConn Health Farmington, CT Marissa Salvo, PharmD, BCACP, FCPA, FCCP Associate Clinical Professor of Pharmacy Practice University of Connecticut School of Pharmacy Storrs, CT
Furthermore, the extensive analysis showed significant reductions in brain natriuretic peptide (BNP), a key, widely recognized blood biomarker of heart failure severity and cardiac distress
Oxidation: Exposure to air can oxidize certain amino acid residues, altering the peptide's structure and function