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People in the clinical trial who did not stick to the strict schedule lost 13.6% of their body weight on average , compared to 16.6% for those who adhered to the protocol

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10.2337/dc18-2584 [DOI] [PubMed] [Google Scholar] Zhao L., Li Z., Vong J., Chen X., Lai H., Yan L., et al

Most over-the-counter pain relievers can be used with semaglutide, but GLP-1 medications increase stomach sensitivity, making NSAID selection particularly important