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Vellekkatt et al.'s double-blind, RCT included 46 MDD patients randomized to standard treatment or a parenteral dose of 3,00,000 IU vitamin D added to standard treatment

Sodium chloride or other tonicity agents are also used to adjust tonicity, if necessary

T.SobiczewskiP.MichalczukL.Wegrzynowicz-LesiakE.MikicinskiA.WolteringE

After 14 days, the mice were sacrificed, and their major organs and tissues were analyzed with a hematoxylin and eosin (H&E) stain (Supplementary Fig

Additionally, the enriched KEGG pathways based on the aforementioned core target genes mainly included neutrophil extracellular trap formation, HIF-1 signaling pathway, longevity regulating pathway, p53 signaling pathway (Fig

Because B12 is water-soluble, excess is excreted by the body