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This review systematically elucidates the multifaceted effects of DM-induced metabolic disturbances on the lung, with a focus on four key pathophysiological axes triggered by hyperglycemic homeostasis, including chronic inflammation, oxidative stress imbalance, endocrine network disruption, and intestinal dysbiosis

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Strains like Lactobacillus and Bifidobacterium support the broader microbiome, while Akkermansia is specifically tied to the gut barrier layer

By improving cellular and mitochondrial function in the brain, methylene blue can also enhance cognition and mood, help combat infectious diseases and reduce inflammation

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