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Ketogenic diet increases transcription of hmgcs-2 (hydroxy-3-methylglutaryl-CoA synthase 2, the key enzyme of ketogenesis) in the brain (135)

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Pickart, GHK-Cu has been shown to activate a plethora of remodeling-related processes including [9]: Chemoattraction of repair cells (capillary cells, mast cells, macrophages) Suppression of free radicals Release of oxidizing iron Increased protein synthesis of collagen, elastin, anti-proteases, fibroblast growth factor, and metalloproteinases

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These metabolite-pathway interactions collectively restore immune balance in lupus models ( Table 2 )