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Second, cancer cells are highly adaptable and can activate compensatory antioxidant pathways, like the thioredoxin system, to survive GSH inhibition, reducing therapeutic effectiveness

Available from: Agency for Toxic Substances and Disease Registry (ATSDR)

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For CDDO-methyl experiments, WT mice without AAV-TBG-Cre injections were injected intraperitoneally with 5 mg/kg of either vehicle (10%DMSO in 90% corn oil) or CDDO-methyl (MedChem Express, HY-13324) for 4 days

Antioxidants, 10(3), 364

Liver tissue from older donors, when exposed to plasma from younger donors, began synthesizing proteins at rates typical of much younger tissue