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Therefore, in this study, we conducted an anti-obesity evaluation using MC4R-deficient mice to clarify whether GLP-1 analogs show anti-obesity effects even in MC4R pathway-deficient models and to determine which of the recently launched GLP-1 analogs is most effective

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The physiological effect of the possible microbial production of alkanes, alkenes, and lysophospholipids near the human gut mucosa will need to be clarified in future studies