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Starting a GLP-1 medication while taking these drugs can still produce weight loss, but the results may be moderated

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( Cell Metabolism , 2022) published the in vitro and in vivo characterization of LY3437943: sub-nanomolar EC 50 potency at all three human receptors, -20% weight loss in obese rats at 4 weeks, and absence of hyperglycemia despite GCGR activation