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Elucidating the contribution of mitochondrial glutathione to ferroptosis in cardiomyocytes

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On the other hand, non-enzymatic antioxidants, including vitamin C, uric acid 42 , bilirubin 39 , vitamin E 43 , and glutathione 44 , directly neutralize free radicals or reactive species, thus protecting biomolecules in serum from oxidative damage

Through pharmacological inhibition, the study further confirmed that NF-B activation was essential for TMAO-induced expression of inflammatory genes and the subsequent endothelial cell adhesion of leukocytes