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Common symptoms include: Nausea and vomiting , particularly after meals or in the morning Early satiety feeling full after eating only small amounts of food Abdominal bloating and distension , often worsening throughout the day Upper abdominal discomfort or pain Heartburn or acid reflux due to prolonged retention of stomach contents Loss of appetite and unintentional weight loss beyond expected therapeutic effects Fluctuating blood glucose levels , as unpredictable gastric emptying affects carbohydrate absorption For most patients on Ozempic, mild to moderate gastrointestinal symptoms are transient and manageable, typically occurring during the initial weeks of treatment or following dose increases

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